The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers less than six a long time of age, because The mix may possibly lead to lethal respiratory depression in this age populace.

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This isn't a whole list of possible Uncomfortable side effects. In the event you discover other Uncomfortable side effects not stated above, contact your health care provider or pharmacist.

There isn't any basic arrangement about precise pharmacological remedy regimens for uncomplicated NMS.

This medication can dry up and thicken mucus with your lungs, making it more difficult to breathe and very clear your lungs. To aid stop this impact, consume plenty of fluids Except if if not directed by your medical doctor.

When doctors prescribe codeine-that contains medications, they need to select the lowest efficient dose for the shortest length of time and should inform their people about these pitfalls along with the indications of morphine overdose. (See Precautions-Nursing Mothers).

The danger for extreme respiration complications is higher when you start this medication, or if you take the wrong dose or choose additional of the medication than prescribed. Taking this medication with Alcoholic beverages or other medicines that could cause drowsiness or breathing troubles may lead to extremely severe Uncomfortable side effects, together with Demise. Also, other remedies can have an effect on the elimination of the products from a human body, which may affect how it really works.

This isn't a whole list of doable Unwanted side effects. If you see other results not shown higher than, Speak to your health practitioner or pharmacist.

Codeine continues to be documented to indicate no evidence of carcinogenicity or mutagenicity in a number of test programs, such as the micronucleus and sperm abnormality assays along with the Salmonella assay. Promethazine was nonmutagenic from the Salmonella exam process of Ames.

Promethazine hydrochloride takes place like a white to faint yellow, pretty much odorless, crystalline powder which bit by bit oxidizes and turns blue on prolonged publicity to air.

Caution clients that some folks have a variation Promethazine codeine syrup within a liver enzyme and alter codeine into morphine extra swiftly and completely than other people. These men and women are ultra-speedy metabolizers and usually tend to have greater-than-standard levels of morphine in their blood following having codeine, which may result in overdose indicators for example extreme sleepiness, confusion, or shallow respiration. Normally, it truly is not known if anyone is really an ultra-immediate codeine metabolizer.

To lower the risk of dizziness and lightheadedness, get up slowly and gradually when climbing from a sitting or lying position.

Promethazine should be used cautiously in individuals with cardiovascular disease or with impairment of liver perform.

It's not a whole listing of possible side effects. For those who discover other Unintended effects not shown earlier mentioned, Call your physician or pharmacist.